Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Lymphatic endothelial transcription factor Tbx1 promotes an immunosuppressive microenvironment to facilitate post-myocardial infarction repair.

Wang, Wenfeng; Li, Xiao; Ding, Xiaoning; Xiong, Shanshan; Hu, Zhenlei; Lu, Xuan; Zhang, Kan; Zhang, Heng; Hu, Qianwen; Lai, Kaa Seng; Chen, Zhongxiang; Yang, Junjie; Song, Hejie; Wang, Ye; Wei, Lu; Xia, Zeyang; Zhou, Bin; He, Yulong; Pu, Jun; Liu, Xiao; Ke, Rongqin; Wu, Tao; Huang, Chuanxin; Baldini, Antonio; Zhang, Min; Zhang, Zhen.

Immunity ; 56(10): 2342-2357.e10, 2023 Oct 10.

Artigo em Inglês | MEDLINE | ID: mdl-37625409

2.

The m6A reader ECT1 drives mRNA sequestration to dampen salicylic acid-dependent stress responses in Arabidopsis.

Lee, Keun Pyo; Liu, Kaiwei; Kim, Eun Yu; Medina-Puche, Laura; Dong, Haihong; Di, Minghui; Singh, Rahul Mohan; Li, Mengping; Qi, Shan; Meng, Zhuoling; Cho, Jungnam; Zhang, Heng; Lozano-Duran, Rosa; Kim, Chanhong.

Plant Cell ; 36(3): 746-763, 2024 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-38041863

3.

The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export.

Chen, Suli; Wang, Ruijia; Zheng, Dinghai; Zhang, Heng; Chang, Xingya; Wang, Ke; Li, Wencheng; Fan, Jing; Tian, Bin; Cheng, Hong.

Mol Cell ; 74(1): 118-131.e7, 2019 04 04.

Artigo em Inglês | MEDLINE | ID: mdl-30819645

4.

Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins.

Ali, Ibraheem; Ruiz, Diego Garrido; Ni, Zuyao; Johnson, Jeffrey R; Zhang, Heng; Li, Pao-Chen; Khalid, Mir M; Conrad, Ryan J; Guo, Xinghua; Min, Jinrong; Greenblatt, Jack; Jacobson, Matthew; Krogan, Nevan J; Ott, Melanie.

Mol Cell ; 74(6): 1164-1174.e4, 2019 06 20.

Artigo em Inglês | MEDLINE | ID: mdl-31054975

5.

DeKinomics pulse-chases kinase functions in living cells.

Weng, Yicheng; Chen, Wendong; Kong, Qian; Wang, Ruixiang; Zeng, Ruxin; He, An; Liu, Yanjun; Mao, Yiheng; Qin, Yunqiu; Ngai, William Shu Ching; Zhang, Heng; Ke, Mi; Wang, Jie; Tian, Ruijun; Chen, Peng R.

Nat Chem Biol ; 2024 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-38167916

6.

Structural and biochemical characterization of the key components of an auxin degradation operon from the rhizosphere bacterium Variovorax.

Ma, Yongjian; Li, Xuzichao; Wang, Feng; Zhang, Lingling; Zhou, Shengmin; Che, Xing; Yu, Dehao; Liu, Xiang; Li, Zhuang; Sun, Huabing; Yu, Guimei; Zhang, Heng.

PLoS Biol ; 21(7): e3002189, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37459330

7.

A new polymodal gating model of the proton-activated chloride channel.

Zhao, Piao; Tang, Cheng; Yang, Yuqin; Xiao, Zhen; Perez-Miller, Samantha; Zhang, Heng; Luo, Guoqing; Liu, Hao; Li, Yaqi; Liao, Qingyi; Yang, Fan; Dong, Hao; Khanna, Rajesh; Liu, Zhonghua.

PLoS Biol ; 21(9): e3002309, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37713449

8.

Integrin α₅ß₁ contributes to cell fusion and inflammation mediated by SARS-CoV-2 spike via RGD-independent interaction.

Zhang, Heng; Wang, Zhengli; Nguyen, Huong T T; Watson, Abigail J; Lao, Qifang; Li, An; Zhu, Jieqing.

Proc Natl Acad Sci U S A ; 120(50): e2311913120, 2023 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-38060559

9.

Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.

Zhang, Heng; Zhou, Bo; Qin, Su; Xu, Jing; Harding, Rachel; Tempel, Wolfram; Nayak, Vinod; Li, Yanjun; Loppnau, Peter; Dou, Yali; Min, Jinrong.

Genes Dev ; 32(5-6): 341-346, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29563185

10.

USP28 Serves as a Key Suppressor of Mitochondrial Morphofunctional Defects and Cardiac Dysfunction in the Diabetic Heart.

Xie, Sai-Yang; Liu, Shi-Qiang; Zhang, Tong; Shi, Wen-Ke; Xing, Yun; Fang, Wen-Xi; Zhang, Min; Chen, Meng-Ya; Xu, Si-Chi; Fan, Meng-Qi; Li, Lan-Lan; Zhang, Heng; Zhao, Nan; Zeng, Zhao-Xiang; Chen, Si; Zeng, Xiao-Feng; Deng, Wei; Tang, Qi-Zhu.

Circulation ; 149(9): 684-706, 2024 Feb 27.

Artigo em Inglês | MEDLINE | ID: mdl-37994595

11.

Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid.

Zhao, Hai-Fan; Meng, Liang; Geng, Zhi; Gao, Zeng-Qiang; Dong, Yu-Hui; Wang, Hai-Wei; Zhang, Heng.

PLoS Pathog ; 19(5): e1011411, 2023 May.

Artigo em Inglês | MEDLINE | ID: mdl-37253057

12.

Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands.

Su, Nannan; Zhen, Wenxuan; Zhang, Heng; Xu, Lingyi; Jin, Yitian; Chen, Xiaoying; Zhao, Cheng; Wang, Qinrui; Wang, Xinyan; Li, Shaowei; Wen, Han; Yang, Wei; Guo, Jiangtao; Yang, Fan.

Nat Chem Biol ; 19(1): 72-80, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36163384

13.

TMK1-mediated auxin signalling regulates differential growth of the apical hook.

Cao, Min; Chen, Rong; Li, Pan; Yu, Yongqiang; Zheng, Rui; Ge, Danfeng; Zheng, Wei; Wang, Xuhui; Gu, Yangtao; Gelová, Zuzana; Friml, Jirí; Zhang, Heng; Liu, Renyi; He, Jun; Xu, Tongda.

Nature ; 568(7751): 240-243, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30944466

14.

Inhibitory mechanism of CRISPR-Cas9 by AcrIIC4.

Li, Xuzichao; Liao, Fumeng; Gao, Jiaqi; Song, Guangyong; Zhang, Chendi; Ji, Nan; Wang, Xiaoshen; Wen, Jing; He, Jia; Wei, Yong; Zhang, Heng; Li, Zhuang; Yu, Guimei; Yin, Hang.

Nucleic Acids Res ; 51(17): 9442-9451, 2023 09 22.

Artigo em Inglês | MEDLINE | ID: mdl-37587688

15.

Targeting heat shock protein 47 alleviated doxorubicin-induced cardiotoxicity and remodeling in mice through suppression of the NLRP3 inflammasome.

Shi, Wenke; Chen, Jiaojiao; Zhao, Nan; Xing, Yun; Liu, Shiqiang; Chen, Mengya; Fang, Wenxi; Zhang, Tong; Li, Lanlan; Zhang, Heng; Zhang, Min; Zeng, Xiaofeng; Chen, Si; Wang, Shasha; Xie, Saiyang; Deng, Wei.

J Mol Cell Cardiol ; 186: 81-93, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-37995517

16.

The structural biology of type III CRISPR-Cas systems.

Li, Xuzichao; Han, Jie; Yang, Jie; Zhang, Heng.

J Struct Biol ; 216(1): 108070, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38395113

17.

Transformation to diffuse large B-cell lymphoma and its impact on survival in patients with marginal zone lymphoma: A population-based study.

Du, Yu; Wang, Ying; Li, Qinlu; Chang, Xiaona; Shen, Kefeng; Zhang, Heng; Xiao, Min; Xing, Shugang.

Int J Cancer ; 154(6): 969-978, 2024 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-37874120

18.

Clinical outcome and molecular landscape of patients with ARID1A-loss gastric cancer.

Sun, Mengyao; Gu, Yun; Fang, Hanji; Shao, Fei; Lin, Chao; Zhang, Heng; Li, He; He, Hongyong; Li, Ruochen; Wang, Jieti; Liu, Hao; Xu, Jiejie.

Cancer Sci ; 115(3): 905-915, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38148578

19.

UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism.

Feng, Xing; Ma, Dong; Zhao, Jiabao; Song, Yongxi; Zhu, Yuekun; Zhou, Qingxin; Ma, Fei; Liu, Xing; Zhong, Mengya; Liu, Yu; Xiong, Yubo; Qiu, Xingfeng; Zhang, Zhen; Zhang, Heng; Zhao, Yongxiang; Zhang, Kaiguang; Hong, Xuehui; Zhang, Zhiyong.

EMBO J ; 39(5): e102541, 2020 03 02.

Artigo em Inglês | MEDLINE | ID: mdl-31975428

20.

Genetic Control of Alternative Splicing and its Distinct Role in Colorectal Cancer Mechanisms.

Zhang, Ming; Chen, Can; Lu, Zequn; Cai, Yimin; Li, Yanmin; Zhang, Fuwei; Liu, Yizhuo; Chen, Shuoni; Zhang, Heng; Yang, Shuhui; Gen, Hui; Jiang, Yuan; Ning, Caibo; Huang, Jinyu; Wang, Wenzhuo; Fan, Linyun; Zhang, Yi; Jin, Meng; Han, Jinxin; Xiong, Zhen; Cai, Ming; Liu, Jiuyang; Huang, Chaoqun; Yang, Xiaojun; Xu, Bin; Li, Heng; Li, Bin; Zhu, Xu; Wei, Yongchang; Zhu, Ying; Tian, Jianbo; Miao, Xiaoping.

Gastroenterology ; 165(5): 1151-1167, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37541527

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